トーマス・ズートホーフ(1955年12月22日)は、ドイツ生まれの生化学者・細胞生物学者。アメリカ合衆国で活躍。膜融合が起こる瞬間を決めるカルシウムイオンの役割を明らかにしました。
経歴
1994 Wilhelm Feldberg Award 受賞
1997 アメリカ合衆国 National Academy Award in Molecular Biology 受賞
2004 MetLife Award 受賞
2008 Bernhard Katz Award 受賞
2008 Passano Foundation Award 受賞
2010 Kavli Prize 受賞
2013 Albert Lasker Award for Basic Medical Research 受賞
2013 ノーベル医学生理学賞 受賞
論文
1. McMahon HT, Missler M, Li C, Sudhof TC: Complexins: cytosolic proteins that regulate SNAP receptor function. Cell 83:111-119, 1995
2. Reim K, Mansour M, Varoqueaux F, McMahon HT, Sudhof TC, Brose N, Rosenmund C: Complexins regulate a late step in Ca2+-dependent neurotransmitter release. Cell 104:71-81, 2001
3. Perin MS, Fried VA, Mignery GA, Jahn R, Sudhof TC: Phospholipid binding by a synaptic vesicle protein homologous to the regulatory region of protein kinase C. Nature 345:260-263, 1990
4. Geppert M, Goda Y, Hammer RE, Li C, Rosahl TW, Stevens CF, Sudhof TC: Synaptotagmin I: a major Ca2+ sensor for transmitter release at a central synapse. Cell 79:717-727, 1994
5. Fernandez-Chacon R, Konigstorfer A, Gerber SH, Garcia J, Matos MF, Stevens CF, Brose N, Rizo J, Rosenmund C, Sudhof TC: Synaptotagmin I functions as a calcium regulator of release probability. Nature 410:41-49, 2001
6. Hata Y, Slaughter CA, Sudhof TC: Synaptic vesicle fusion complex contains unc-18 homologue bound to syntaxin. Nature 366:347-351, 1993
7. Verhage M, Maia AS, Plomp JJ, Brussaard AB, Heeroma JH, Vermeer H, Toonen RF, Hammer RE, van den Berg TK, Missler M, Geuze HJ, Sudhof TC: Synaptic assembly of the brain in the absence of neurotransmitter secretion. Science 287:864-869, 2000